SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8a64986f8959c86f158f878ba563f4a2aa74d8bf4e13caf58590308475e9a3' 
  AND token = 'i2v+SfShzxlvh3dgOa5WNUdKIOhT8WGiUOdDLWyPj+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}