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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7dfc801f0dd0c1a5bdd488a9826dcf892a72309cc12c3e2a708149fe66cdbd' 
  AND token = 'ADePuGDizRC2EAqBkh0MdszWphmtV3JAHV2m+ANwyO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}