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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8466a37b12a628f9dc6d36cf979905a2741b7195597e24125915c7efa580c6a' 
  AND token = 'JZn8uy64Gw2qN7HhLXXOhH1ojI1mGNpvmthlN992MbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}