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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '890c520369284805a664c96bdb313c164d21b669df942ebcf9b4cc982034cc55' 
  AND token = 'WcYwBoUm4bblTTZEKVNTK6KNPP0PDHQwyXwxCbvJy0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}