SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db6cd9ea6fc220958efed6258153126f9bdddcb6535a92456a0602b1a75a0760' 
  AND token = 'A281VTZ9iR+zb6WsfeFS0wEmgdA5oLUgvl8PK57xl98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}