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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d6b5cd2893741dab50e2b2b4a5a4edb4ce3ba7ea40f9cf96c328634525a341b' 
  AND token = 'cwcqBofgQnRTdmrDsjdg785YhpKp1hpZpcZGlmEURXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}