SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3333eaeb5412578c9d26e5a76d47332104e2a82ea04d4512e068d8ef89cc11' 
  AND token = 'o2xoQg5vTn7fWsFLGDsSjXe55lgTSkhjgS8Oavo6ehY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}