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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e6c4327bce5a6fddb3cfe564a78d4e0f714c0737054fc62c7f98560d815ab3' 
  AND token = '/VAMYmxXA4u2on+mX7OsXMWGa3+kf0TtbMax9/Z0mRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}