SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa4ae5943bfd566f2bd9588c2481934a4feea827a4d96aa72bab38f2dc50182' 
  AND token = 'QWeI8UlV+GPdx5SXxkTz1o+ZjPdHKaUNFmda4Pesms0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}