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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181e0fed05b4480b8d7dd3ff154af5033812c97f52275f12a423e785a23293a3' 
  AND token = 'oUG+kKWbfrsMB3zJ49Pqtn7tVuYtuORlHRAmRJ0WzCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}