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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18e7fa2516618147a22d972941f1fd0d72777789e9dfa140b73b4e11536bfe4' 
  AND token = 'D/i4SdyvCVWgB9kd+dKLLs5GnRKDHd6uILlUd/e3pyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}