SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a222cc7a062dc3957cbb595315239e2829970331ff9602f1b0e2901fde76ec0b' 
  AND token = 'a30p4Oasrh0TCFFSB0BPAgeY2cpTqR1yiYdO+9CMDOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}