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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c737d3eece29e083dfe7a348efb72e770fcf23e53d207cde51fa871df00e643d' 
  AND token = 'CL1xxLVfWu6RoXkNurG+oJSE2lIOvVK949ysp9ckUVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}