SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b1f616073e086d5cc4e2213e0e960501ae7055c3eb9e9b14a4c580653842a2' 
  AND token = 'Xnvw0jSdPQgn7OUFjmNrZs57V86nGLRCtXe59lAIsvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}