SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d2df7239ea18be39c8954beaadbdb4fb2834b60ea120ee26686ad02c47c6c6b' 
  AND token = 'aLWlfxSnuaErIYiBsugDV2NlVBdjIPRzMmmy1/So7XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}