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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d092b993ae4c061e99e0fd7b5ea51f45e0cd4a5124a184804f40d19b47ace1e' 
  AND token = 'PyYLB3SwZSYz3MKqpRLyrMvvnm6ZyAJutsXHQBDbcUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}