SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82bd59b7b11204816ce650b8841d3d9209b73bce14e500f71ed948bd9df0145e' 
  AND token = 'TcrLGZ3JTyvyv7xY4L1RUQVBl2W2Zd0wHFAQataHq1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}