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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129be89e48c0fdb29910c500ad7cd6783bf9c3d923e3893880ca0de82af851f7' 
  AND token = '+1A819WuyPYIan2NOs5OnXaBkMAhujGq48Yz4azTZtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}