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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f63f6f93b8aa9a6ee57d71136b571b1afd14da302a9a4f4134b22e4d2b714010' 
  AND token = 'FGe7sJmpDPIGN+vvL1Jv/+87XGv8m5WBFtlEEpNzOsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}