SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e1474b20271cf1df2e509da6f9c7d6e8a8f441ee1e213f3276affa680854f23' 
  AND token = '/F+RuHLsoc7sKZ0OV8Q1a+XEPG+Cccix2xRxQwO3gKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}