SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '432af1b6aabc9ba4697fbd98258dd429351b976945530bca094afc9345a55561' 
  AND token = 'T0dVaMZf4Np6q1UZ23PmMurI64JJx7aExkg9HN2HRH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}