SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1519ed69c01ad746dcb85f237cfcf6d85346974b5e80939ae962e368f65bcc2' 
  AND token = 'm1qOtLB2/mFan6DRT9oC26KFaJTsTNLjlPPq/ww/8dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}