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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545cb5a375cecadab0da1ae692b4d26714abb65744e02fe00dae191ece5cba03' 
  AND token = 'IrnyIzd8YsrAS6qV7ML2k/ldoAC81n9zQ+HRNYGvXPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}