SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053946fb9900dce9cc092915a9fdc8a067117e8d81b165b4fd0d0e80dbf182dd' 
  AND token = 'ytj85hVO5k1wJW/2TswjT3MS6pWiCDWmR/wrMFmnLRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}