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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c81a903676b55df520d7ac06fd97a055631f7a8b1313ce8b01ee9d7a30f2e6c' 
  AND token = 'cG+gIEVBGx2vRb6xiEQckAytGQEXH5TA3wNOm/Ur9NU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}