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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c90a197468bfdfea1fc26c786c2f021532656cdf9ed7c6fc6d857420a6f57a2' 
  AND token = 'DALJLONGfsWbLDt9m8286Yjv9rZaJkLk5nww4azMO0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}