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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06acd04f39cad112a496fe7b5457da2b0a3deb023433f15856ed78c1f899d3aa' 
  AND token = 'fQSvIJzmXNw7nEqJI1CZM19jPaHaLEOCMPlEIEaLtuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}