SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4266fb6a51a8b7918e4eb3d03d55bab07b77edb81b988942b594fdeeda0f1456' 
  AND token = '3zAo3k7no5q239vua+4Uex8fMitWGzpQs2zVzOud1ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}