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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea9f457ab6d5068b8300c0c13f902064242e3d44d188ea535d98221e695f671' 
  AND token = 's2mZEVnzecrfpGbuVEnZ8gPVrP+b8mL0o9MNT42WQ7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}