SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d8da54d6081c84475d4f9f714e1850cef11095944e43a6d546effaa9940bf3' 
  AND token = 'hcRFHE+MvxVvwOF4mS61y/gYHpiWaHT0vmZz+YuiPm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}