SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0cae161215f5029d9bf6664469a18e4f2bcea53792030e1ea03326a52d8d207' 
  AND token = 'y15pcBZQI/lxVD34DrdxoOMAbOyXhFhmqSariia62HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}