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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4487e29d3e5ccbf58155ba255f6e39df4fc532ddfd7bb046755fdc66465f7c2' 
  AND token = '1ZeqynDRRBwHUAwXN/WmUze729CNmakFlo1RGY9T+CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}