SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76f7be674bac36782f18a3d0bfc978086bc5ffdd01f1ff29e22b7a967d884ae5' 
  AND token = 'Za42fzSsxgrOkvSX4xoXrDjp5XfLwjToMFVD7Yf+xfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}