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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a78b435229f6df02a5204e936b396d744aceeda7a2905f51a44491e387d467' 
  AND token = '0RXUXzrnMqZ6lp3TWW+uwmCVlEPQX297FgpF4LF1LMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}