SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24f40b39d34e47d2a865e4da9d9339abb6fbaec55ce9e816516e710814574433' 
  AND token = 'MSAw51NzHz2k/lUUeOmNcQRsaBxBBeokm56viiyAHJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}