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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72850a25a7bd35e8492e06465d634a2ed895f82c3b8b1990c283677725955bf1' 
  AND token = 'gnhl0AxIGO95AVKkAUZg6sQbcEHdh2uRZJxH9DT9ors=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}