SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072381ae201c560c88d6613cc77873b83ace382eb99131e88d2152089f1c32f6' 
  AND token = 'CHZX9/ZDt+igm7xISzlAdo1KgJGajVQlePYpnIb8odU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}