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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66406f7053bb27cc3f855b27ab031dae102f33044c47cc840ed5cc86a0d34ab9' 
  AND token = 'r4OqYG0eIhdQM6I+/csNL4EaOB1PAKmg2EyRDG5ibUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}