SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f081d4bbb87f8b9e7149803ba28649c69b97014fd6f756533d4c284469d799b9' 
  AND token = 'RftRazClRNafwokyrcYJmKlS+ZLBc8AjoMAEtLeh6e4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}