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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81fd678923c9a549757d022e0a2e86129f971bee5cbc0abd1cac9414d784dfc0' 
  AND token = 'tdT8ljIK8iwGdLfsznYOC8a6NRRiFQckDLgqNmrClBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}