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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64cc69a841593d26f63a68a35159f7191d434f30dd8d272153da9ab636577d76' 
  AND token = 'URFdzQR56ce6QUQ9PvlnVrU5y1q6KNdD027wlxUZD+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}