SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0886140bbb867590fea8565e16fdd329dede8f14f9f7ad0d337c7a9c1b086b09' 
  AND token = '3OP/qjz8+I9NuFhq0YwXW/RpzdKtNtw5uDEfmE95EBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}