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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5cc89d21e4b09539e6f34ac6c404f54adc48c4c082cfec75f1378f52b8f506' 
  AND token = 'tupzfByZ2ZrcqToOy7ANe4OxZEl8ZZ3bK8bj/x/BCdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}