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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a89d548ad7afff0800dcc702d0a3670e96e604689ca8a92da766c6270ca92e84' 
  AND token = 'r7JrbEE7SIiUgR5Npg7Oyc1zChVPuiJrfdaRK4//EZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}