SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '447a3ac2e1c4c342bc7230cbdbec4fef25aae0988027d5d5bbc3ed0221905cbf' 
  AND token = 'o6DppQvZ0/T/bcQYHEu6k1kmV/0nLChCgdoTDEzbqJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}