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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f8ba10100ac73fb3bcf2ea06c99b0b5f81fa69203935f436a35540f0bf01233' 
  AND token = 'tJqsgIRVy+AaFmWg2rs4E4u7idXfuYUsqkM59USAhO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}