SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea86a77aa85b248c8f99e56c2e545dc285c8bc75d6c5be91a077301aa207765f' 
  AND token = 'JFNanWrDMwhFN9B12SnE1phlAzmtSjRbcaghFItmmFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}