SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2e63983db79389f10fd07ebab99a5786f387679d7f2fc01e7ed9f27678c65e5' 
  AND token = 'NGkg/znh56qH1MQZqRZA+slaQIVrzyrh1AcVDWU51ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}