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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3214aca608cab143a516af22e14cb0238a98b1a68a850633f1524755eb015ea2' 
  AND token = 't1+Q8xxps7QBtAe0naCRcefg23I5vtbdx7zzRlLUQso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}