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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd929fd287ee18f07e274f634dc0fc9592a1a594b70c8b0cf158962a02d24d384' 
  AND token = 'epm/ydhc5qn4AQAYJyVxFizCFMw5HfRZpzYsw19aWEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}